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Cantargia AB | 961 followers on LinkedIn. A Swedish listed biotechnology company | Cantargia develops antibody based therapy against the target IL1RAP. The lead candidate CAN04 is for treatment of 2020-04-07 Cantargia AB today announced the submission of a clinical trial application investigating antibody CAN04 in combination with FOLFIRINOX for first line treatment of metastatic pancreatic cancer (PDAC). Cantargia is developing the humanised antibody CAN04, against the target molecule Interleukin-1 Receptor Associated Protein ("IL1RAP"), for treatment of cancer. Cantargia has previously shown that Cantargia has announced that its research platform CANxx has progressed with the start of a drug development project, CAN10. The project originates from inhibition of three inflammatory cytokine systems (IL-1, IL-33 and IL-36) by antibody targeting of interleukin 1 receptor accessory protein (IL1RAP). An opposition has been filed against one of the European patents in Cantargia’s patent family covering antibody therapy in solid tumors.

Cantargia il1rap

The basis for this is the protein IL1RAP that is involved in a number of diseases and where Cantargia has established a platform. More information about Cantargia is available at www.cantargia.com. About CAN04 The antibody CAN04 binds strongly to the target IL1RAP and functions both though ADCC as well as blocking IL-1α and About Cantargia Cantargia AB (publ), reg. no. 556791-6019, is a biotechnology company that develops antibody-based treatments for life-threatening diseases.

Cantargia - Aktieraketer.se

2018 — Cantargias andra projekt är i forskningsfas med målet att utveckla en IL1RAP bindande antikropp optimerad för behandling av autoimmuna och Lundabolaget Cantargias målsökande robotar angriper tumörer på nytt sätt Cantargia har utvecklat en antikropp, riktad mot IL1RAP, som i prekliniska studier Cantargia meddelar positiva prekliniska data för CAN04 i urinblåsecancer Målmolekylen för CAN04, IL1RAP, har påvisats på cancercellerna hos cirka 80% av 10 okt. 2019 — Forskningsbolaget Cantargias patent som skyddar antikroppar mot IL1RAP i tumörformer har fått konkurrenten Mab Discovery att lämna in Cantargia develops antibody based therapy against the target IL1RAP.

Cantargia erhåller patentgodkännande i Kanada och breddar

It is developing two antibodies against IL1RAP, nidanilimab (CAN04) and CANxx. Nidanilimab is being studied in a Phase I/II CANFOUR in solid tumours focusing on NSCLC and pancreatic cancer.

Cantargia förvärvar patentportfölj runt IL1RAP från Cellerant tis, mar 10, 2020 08:45 CET. Cantargia AB meddelade idag förvärvet av en patentportfölj från Cellerant Therapeutics Inc vilken täcker olika aspekter runt ”interleukin 1 receptor accessory protein” (IL1RAP).
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Den förvärvade patentportföljen inkluderar ett amerikanskt patent kring IL1RAP som måltavla för antikroppsterapi inom leukemi. IL1RAP • Three different systems signal through IL1RAP • These systems contribute to various inflammatory diseases • Can be blocked by antibodies against IL1RAP 29 Cantargia partnership with Panorama Res Inc (Sunnyvale, CA) Cantargia utvecklar en antikroppsbaserad behandling riktad mot målmolekylen IL1RAP som har potential att användas för ett flertal olika cancersjukdomar. Cantargia förvärvar patentportfölj runt IL1RAP från Cellerant tis, mar 10, 2020 08:45 CET. Cantargia AB meddelade idag förvärvet av en patentportfölj från Cellerant Therapeutics Inc vilken täcker olika aspekter runt ”interleukin 1 receptor accessory protein” (IL1RAP). Cantargia AB meddelade idag förvärvet av en patentportfölj från Cellerant Therapeutics Inc vilken täcker olika aspekter runt ”interleukin 1 receptor accessory p Cantargia förvärvar patentportfölj runt IL1RAP från Cellerant | Placera Cantargia acquires Cellerant IP on IL1RAP Tue, Mar 10, 2020 08:45 CET. Cantargia AB today announced the acquisition of a patent portfolio from Cellerant Therapeutics Inc covering aspects around the interleukin 1 receptor accessory protein (IL1RAP). STOCKHOLM (Nyhetsbyrån Direkt) Forskningsbolaget Cantargia köper en patentportfölj kring IL1RAP som måltavla för antikroppsbehandling inom blodcancerformen leukemi från Cellerant Therapautics.

2017 — Cantargia har godkänt patent på antikroppsbehandling mot IL1RAP och vi är inte medvetna om några konkurrenter som bedriver kliniska 3 maj 2018 — Det godkända patentet med patentnummer CA 2,772,111 avser Cantargias metod med IL1RAP som målmolekyl för antikroppsbaserad terapi 4 dec.
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Cantargia: Novartis's CANOPY-2 trial disappoints - Edison

View full The basis for this is the protein IL1RAP that is involved in a number of diseases and where Cantargia has established a platform. The main project, the antibod. 10 Aug 2015 Cantargia AB is the owner of the intellectual property rights for agents targeting IL1RAP for use in the treatment and diagnosis of neoplastic Cantargia develops a therapy for the treatment of cancer by targeting a unique cell-surface receptor on malignant stem cells. 15 Mar 2021 It is developing two assets against IL1RAP, CAN04 and CAN10. The lead clinical trial is a Phase IIa CANFOUR study with CAN04 in non-small IL1RAP is overexpressed on candidate AML stem cells and is a promising target for Cantargia AB is the owner of the intellectual property rights for agents M.J. and T.F. are cofounders and have equity ownership in Cantargia AB (Ideon To study the expression of LSC markers in more detail, IL1RAP, CD25 and. 2 Jun 2019 Cantargia $CANTA CAN04 (anti-IL1RAP) phase I #ASCO19 1/4 good safety profile. 0% ORR/ 43% CBR for the dose-escalation monotherapy CAN04 is a first-in-class fully humanized monoclonal antibody targeting IL1RAP, a co-receptor for the IL-1 receptor which is expressed on human cancer cells.

R Cantargia förvärvar patentportfölj runt IL1RAP från Cellerant

no. 556791-6019, is a biotechnology company that develops antibody-based treatments for life-threatening diseases. The basis for this is the protein IL1RAP that is involved in a number of diseases and where Cantargia has established a platform. Cantargia develops antibody-based pharmaceuticals against interleukin-1 receptor accessory protein (IL1RAP). The lead project CAN04 is in phase IIa clinical development for treatment of cancer while CAN10 is in preclinical development towards autoimmunity/inflammatory diseases. Cantargia develops antibody-based pharmaceuticals against interleukin-1 receptor accessory protein (IL1RAP). The lead project CAN04 is in phase IIa clinical development for treatment of cancer Besides the patents that Cantargia already owns, there is one additional patent on IL1RAP as target for antibody-based therapy in hematological cancer: US patent no.

Cantargia develops antibody-based pharmaceuticals against the interleukin 1 receptor accessory protein (IL1RAP). The lead project CAN04 is in phase IIa clinical development for the treatment of pancreatic cancer and non-small cell lung cancer. With the CANxx platform, the goal is to build on the platform of novel IL1RAP-binding antibodies. Cantargia's vision is to develop and secure the new generation of targeted medicines against IL1RAP as an important part of tomorrow's more effective cancer treatments. The vision also includes developing new product candidates with the potential to treat even autoimmune / inflammatory diseases. Cantargia’s antibody CAN04 binds IL1RAP with high affinity and functions through both Antibody Dependent Cellular Cytotoxicity and blockade of interleukin 1 signaling.